Unless we have significant advances in technology it will be several years, if not decades, before humans land on Mars. Some of the issues we face are:
Length of flight to Mars and the severe toll that weightlessness places on the human body.
Maintaining environmentals (e.g. oxygen, food, medical issues) for what will be a three year mission.
Landing a craft on Mars has proven to be difficult. Using parachutes is pretty much out of the question due to the thinness of the martain atmosphere and the speed that the landing craft will be subjected to (parachutes could be ripped to shreds). Plus dust storms with the speed of their winds could make any type of landing difficult.
For a trip of this length, phsychological issues will definitely come into play. The rocket jockies of the type seen in Mercury, Gemini, Apollo and shuttle missions would not make good crewmen for that type of journey.
Survival on Mars itself would be challenging as well. Dust storms, frigid temperatures, hazardous terrain and solar radiation to name a few are going to present a whole new set of problems.
Probably the biggest obstacle is going to be the cost. It would certainly have to be an international effort to spread the cost around. I don't see any significant signs of cooperation on even planning such a mission let alone accomplishing it.
If I had to make an educated guess, we will be lucky if we get there by 2030. I would suspect it will be closer to 2040 unless there are significant improvements in the political and scientific arenas.